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The answer lies in The very fact there are multiple isoforms of every troponin subunit that are encoded by distinctive genes, several of which might be expressed selectively in cardiac muscle. While TnI and TnT have unique cardiac and skeletal isoforms, they share a standard isoform of TnC: the gradual-twitch skeletal muscle isoform (ssTnC) (Some s
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Apart from false-optimistic effects, heterophile antibodies may cause falsely lower effects whenever they bind to the variable regions of the capture antibody, mimicking the antigen to become measured and stopping troponin from binding.[89] The most commonly used method for reducing the impact of HAMA on commercial immunoassays will be the addition